Coffee ground vomitus refers to a particular appearance of vomit. Within organic heme molecules of red blood cells is the element iron, and when this iron has been exposed for some time to gastric acid, it becomes oxidized. This reaction causes the vomitus to look like ground coffee. Coffee-ground vomitus is a sign of possible upper gastrointestinal bleeding. Esophagitis or gastritis, for example, may bleed and produce coffee-ground vomitus. When unaccompanied by melena, hematemesis or a fall in hemoglobin with corresponding urea rise and stable creatinine, other causes of coffee ground vomitus need to be elucidated; for example gastric stasis, bowel obstruction or ileus, that can cause oxidised food material to be vomited. Vomiting iron supplements can also mimic coffee grounds to the untrained eye. When attributed to peptic inflammation, use of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective serotonin reuptake inhibitors (SSRIs) are commonly implicated. These drugs can interfere with the stomach's natural defenses against the strongly acidic environment, causing damage to the mucosa that can result in bleeding. Therefore, it is recommended that these class of drugs be taken with food or on a full stomach. Other causes of inflammation may be due to severe gastroesophageal reflux disease, Helicobacter pylori gastritis, portal hypertensive gastropathy or malignancy.
When bright red blood is vomited, it is termed hematemesis. Hematemesis, in contrast to coffee ground vomitus, suggests that upper gastrointestinal bleeding is more acute or more severe, for example due to Mallory-Weiss tear), gastric ulcer or Dieulafoy, or esophageal varices. This condition may be a medical emergency and urgent care may be required.
Oxidized blood from an upper gastrointestinal bleed can also be excreted in stool. It produces blackened, "tarry" stools known as melena.
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Source of article : Wikipedia
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